If you ask me it's based upon how long you stay in combat. When I first interlock I find I'm getting penalized, however, after a few rounds the rolls go green and by far higher (ive rolled 240's before in red and anything up to 360 in green). However, its very hard to get to this stage, especially since an Martial Artist can just attack you once and you've lost your guns, and it just restarts the process from there. When I was using dual pistols i was getting penalized so often that I loaded Consistant Technique, so that when i was penalized, it wasn't too bad.
Overall, gun rolls are the most random of all, one second you can be outrolling and MA, then the next a Hacker can out roll you. And as for Dodge Ranged, I can activate Line up the shot and Steady Aim, and still miss a lot of shots (this normally goes for Force Multipliers and Upgrade Masters).
Also, I'm pretty sure you get penalized for shooting at someone who is in interlock. But on the other hand, some gunman moves can do a lot of damage (especially full auto redux) and are best used for support roles, although Expert Rifleman and Sniper can be a good solo load if you know what your doing.