Vista has some graphical issues with MxO, but to decrease them, do the following:
*Run latest DirectX (available from Microsoft)
*Install latest drivers / catalyst
*Disable all ingame shadows
*Save this file to your MxO directory (disables dynamic lighting, right click save as.)
*(since you have Vista Buisness) In the MxO Folder, rightclick->properties on launcher.exe, and matrix.exe. Go to the Compatibility Tab, and select XP Compatibility, and Disable Desktop Composition (disables Aero while you play).
Should prety much cover it.